Idiopathic or iatrogenic membranous glomerulonephritis? A case of spironolactone-induced membranous glomerulonephritis

Idiopathic or iatrogenic membranous glomerulonephritis? A case of spironolactone-induced membranous glomerulonephritis

Membranous nephropathy (MN) is the most common cause of nephrotic syndrome in adults in the UK. In most cases, the aetiology remains unknown, although recent data suggested a clear mechanism of pathogenesis. In approximately a quarter of cases, however, a presumed cause is found, such as systemic lupus nephritis, malignancy, hepatitis B and various drugs. Here, we present a patient who develope...

Idiopathic membranous glomerulonephritis: aspects of geographical differences.

Clinicopathological studies of 89 cases of idiopathic membranous glomerulonephritis was carried out to investigate the clinical and histopathological characteristics of the disease. The results were compared with those of previous published reports to observe whether any difference between Japanese and caucasian patients exists. There were no obvious differences as to main clinical features, al...

Complete remission in idiopathic membranous glomerulonephritis.

Pulmonary Embolism Revealing Idiopathic Membranous Glomerulonephritis

We describe a case of a 55-year-old man who presented with pulmonary embolism and who was found to have nephrotic syndrome due to idiopathic membranous nephropathy. There are no other signs of nephrotic syndrome such as edema.

Extensive crescent formation in idiopathic membranous glomerulonephritis. A case report.

Idiopathic membranous glomerulonephropathy is a well defined clinical and pathological entity (Cluck et al, 1973). It is postulated to be an immune-complex disease. There seems to be some variation in the life expectancy in this group of patients, nonetheless most agree that slow progression to renal failure is usual. Evolution of membranous nephropathy to a rapidly progressive crescentic glome...